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Argipressin CAS: 113-79-1 AVP BETA-HYPOPHAMINE

Kufotokozera mwachidule:


  • CAS NO:113-79-1
  • Dzina:Argipressin
  • Chemical formula:Zithunzi za C46H65N15O12S2
  • kachulukidwe:1.59±0.1 g/cm3(Zonenedweratu)
  • Fp:113 ℃
  • kutentha kutentha.:2-8 ° C
  • pka:9.90±0.15(Zonenedweratu)
  • PH:~3.5
  • mawonekedwe:ufa
  • Molar mass:1084.24
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    Kugwiritsa ntchito

     

    [Arg8] -Vasopressin yankho linagwiritsidwa ntchito ngati antigen pokonzekera preadsorbed antisera ya immunocytochemistry.Chogulitsacho chinagwiritsidwa ntchito mu L6 cell chikhalidwe cha C5 subclone pa maphunziro osiyanitsa.

    Chifukwa ndiyokhazikika, desmopressin imakondedwa pazithandizo makamaka ngati zotsatira za pressor sizikufunidwa.Chizindikiro chachikulu cha chithandizo ndi matenda a shuga a insipidus, matenda omwe amayamba chifukwa cha kuchepa kwa ADH ndipo amadziwika ndi polydipsia, polyuria, ndi kutaya madzi m'thupi.Desmopressin imagwiritsidwanso ntchito pochepetsa kukomoka kwa usiku, kapena kukodzera pabedi, mwa ana.Ndiwothandiza kwa anthu omwe ali ndi hemophilia yofatsa A kapena omwe ali ndi mitundu ina ya matenda a von Willebrand, pomwe chinthu cha von Willebrand chimapezeka pamilingo yotsika.Pazifukwa izi, desmopressin imaperekedwa pamene magazi ambiri atuluka kapena asanachite opaleshoni kuti athandize kuchepetsa kutuluka kwa magazi m'njira zina mwa kuonjezera kuchuluka kwa coagulation.Zotsatira zoyipa za desmopressin ndi kuledzera kwamadzi ngati mutamwa kwambiri.
    Otsutsa a ADH, kuphatikiza ma analogue a nonpeptide omwe angatengedwe pakamwa, apangidwa molunjika pamtundu uliwonse wa zolandilira.M'tsogolomu, omwe amaletsa ma V1 receptors angakhale othandiza pochiza matenda oopsa, ndipo omwe amaletsa ma V2 receptors angakhale othandiza pamtundu uliwonse wa kusungirako madzi mopitirira muyeso kapena hyponatremia, zomwe mpaka pano palibe chithandizo chokwanira chochiritsira.

     

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