China Hot Sale CAS 2160555-52-0 5CAKB48 cannabinoids mphamvu yoyera

Chemistry

5F-AKB48, kapena N-(adamantan-1-yl)-1-(5-fluoropentyl)-1H-indazole-3-carboxamide, ndi indazolecarboxamide yopangidwa chifukwa ili ndi gulu lolowa m'malo la indazole.Indazole moeity iyi imalowetsedwa m'malo ndi R1 ndi tcheni cha fluoropentyl, m'malo mwa 5F-PB-22.Kuphatikiza apo, indazole imasinthidwa kukhala R3 ndi gulu la carboxamide.Gulu la carboxamide ili ndi N-lolowetsedwa m'malo mwake gulu la amine ndi gulu la adamantane.Gulu ili lili ndi mphete zinayi zosakanikirana za cyclohexane mumtundu wapadera wotchedwa diamondoid.5F-AKB48 ndi analogi wa STS-135 momwe maziko a indole amalowetsedwa ndi maziko a indazole.

Zotsatira zathupi

Zomverera modzidzimutsa

"Thupi lapamwamba" la 5F-AKB48 lingathe kufotokozedwa kuti ndi lakuthwa, losasangalatsa, lozungulira, komanso lamagetsi lamagetsi lomwe limafalikira pa thupi pambuyo poyamwa koyamba.Imasunga kukhalapo kokhazikika komwe kumakwera msanga ndikuyambanso ndikugunda malire ake pomwe pachimake chafika chisanathe msanga.

Kuwonongeka kwa magalimoto -

Izi zimapangitsa kuponderezedwa pang'ono kapena pang'ono kwa mphamvu zamagalimoto zomwe zimakula molingana ndi mlingo, koma nthawi zambiri zimabweretsa kulephera kwathunthu kuyenda ndi kuchita mayendedwe oyambira.

Kuwonjezera chilakolako

Monganso ma cannabinoids ena ambiri, 5F-AKB48 imayambitsa kuchulukirachulukira, komwe kumadziwika kuti "munchies" pachikhalidwe chodziwika bwino cha ku America ndi United Kingdom.Kafukufuku wazachipatala komanso kafukufuku wazachipatala apeza kuti cannabis imawonjezera chisangalalo cha chakudya komanso chidwi ndi chakudya.Izi zimaganiziridwa kuti ndi chifukwa cha momwe endocannabinoids mu hypothalamus imayatsira ma cannabinoid receptors omwe ali ndi udindo wosunga chakudya.

Kuthetsa ululu

Cannabinoids awonetsedwa kuchipatala kuti apereke mpumulo wopweteka kudzera mu agonism ya cannabinoid receptors CB₁ndi CB₂, yomwe imafikira ku synthetic cannabinoid receptor agonists.

Kuzindikira kupepuka kwa thupi

Kusintha kwa mphamvu yokoka

Kutaya madzi m'thupi

Izi zimatchedwa colloquially monga "cotton mouth" mu chikhalidwe chodziwika cha America ndi United Kingdom.

Vasodilation