China Hot Sale CAS 7361-61-7 Xylazine cannabinoids ufa woyera

Kufotokozera

Xylazine ndi agonist wa α2-adrenergic receptors (Ki = 194 nM).Ndi analogue ya clonidine, α2-adrenergic receptor agonist yomwe imagwiritsidwa ntchito kuchepetsa kuthamanga kwa magazi.Xylazine imagwiritsidwa ntchito pa sedation, anesthesia, ndi analgesia mu zinyama zomwe si zaumunthu.Chogulitsachi chimapezekanso ngati mulingo wowunikira.
Woyambitsa Xylazine, Bayer

Ntchito

Antinociceptive; Alpha-2 adrenergic agonist
Ntchito

Xylazine ndi gulu la α2 la adrenergic receptor agonist.Xylazine ndi clonidine analoque yomwe imagwira ntchito pa presynaptic ndi postsynaptic receptors monga 2-adrenergic agonist.
Njira Yopangira

2,6-Dimethylphenyl isothiocyanate, 31.0 g (0.2 mole), yokonzedwa kuchokera ku 2,6- dimethylaniline yokhala ndi thiophosgene, inawonjezeredwa dropwise mkati mwa 15 min kuyimitsidwa bwino kwa 15.0 g (0.2 mole) ya 3-aminopropanol-1 mu 100 ml ya ether.Ether inayamba kuwira.Kukondoweza pansi pa reflux kunapitilizidwa kwa mphindi 30, ndipo ether imachotsedwa.Chotsaliracho chinathandizidwa ndi 100 ml ya concentrated hydrochloric acid ndikuphika pansi pa reflux kwa mphindi 30.Pambuyo kuziziritsa, imachepetsedwa ndi madzi, osasefedwa opanda zinyalala, ndipo mazikowo amawonjezedwa ndi kuwonjezera kwa sodium hydroxide solution.Pamene recrystallized kuchokera benzene-ligroin, chifukwa pawiri 2-(2,6- dimethyl-phenylamino) -4H-5,6-dihydro-1,3-thiazine, zisungunuke mfundo 140-142 ° C (zokolola 90% ya theoretical). ).
Ntchito Yochizira

Analgesic, anesthesia

Kufotokozera Kwambiri

Xylazine imasungunuka mu methanol (50 mg / ml), ikupereka njira yomveka bwino, yopanda mtundu.Amasungunukanso mu HCl acid komanso mu chloroform.Xylazine imakhala yosasungunuka m'madzi komanso m'madzi amchere.
Zochita za Biochem/physiol

Xylazine ikagwiritsidwa ntchito limodzi ndi ketamine imaonedwa kuti ndi mankhwala opha tizilombo amphamvu komanso otetezeka mu nyama yoyesera.Amadziwika kuti amakweza kutulutsidwa kwa shuga m'chiwindi, zomwe zimakulitsa hyperglycemia.
Njira yochitira

Xylazine imagulitsidwa ngati mchere wa hydrochloride monga Rompun (100 mg / mL) ndi Anased (20 mg / mL) jekeseni njira zoyendetsera mtsempha kwa akavalo ndi agalu, motero.Zochita za xylazine zikhoza kusinthidwa ndi kayendetsedwe ka yohimbine, indoalkylamine alkaloid, yomwe imalepheretsa ma α2-adrenoreceptors omwe amalimbikitsidwa ndi xylazine.
Mbiri Yachitetezo

Poizoni pomeza, subcutaneous, ndi kudzera m'mitsempha.Zotsatira za machitidwe aumunthu: kusintha kwa kayendetsedwe ka magalimoto, kutsika kwa magazi, miosis, pleural thickening, kuchepa kwa kugunda kwa mtima, kugona.Ikatenthedwa kuti iwonongeke imatulutsa utsi woopsa kwambiri wa NOx ndi SOx