Mankhwala othana ndi khunyu Mankhwala Gulu Pharma Pakatikati Kugulitsa Powder Mapiritsi a ufa CAS 148553-50-8

                                               Kugwiritsa Ntchito CAS 148553-50-8:

CAS 148553-50-8 ndi analogi wa neurotransmitter gamma-aminobutyric acid (GABA), wogulitsidwa pansi pa dzina lamalonda.Mu Disembala 2004, a FDA adavomereza CAS 148553-50-8 ngati mankhwala ochizira matenda a diabetesic neuralgia ndi herpes zoster neuralgia.CAS 148553-50-8 ndi mankhwala oyamba kuvomerezedwa ndi ku United States ndi Europe kuti azichiza pamwamba pa mitundu iwiri ya ululu.Mu June 2005, CAS 148553-50-8 inavomerezedwa kuti ichiritse adjuvant chithandizo cha khunyu.Mu Marichi 2006, European Union idavomereza CAS 148553-50-8 kuti athe kuchiza matenda amtundu uliwonse wa nkhawa (GAD) komanso matenda ovutika maganizo (SAD).
              
CAS 148553-50-8 imagwiritsidwa ntchito makamaka pochiza zotumphukira neuralgia ndi adjuvant chithandizo cha kukomoka kwapang'onopang'ono.
CAS 148553-50-8 ikhoza kuchepetsa kutulutsidwa kwa ma neurotransmitters omwe amadalira calcium posintha magwiridwe antchito a calcium.Ngakhale CAS 148553-50-8 ndi yochokera ku inhibitory neurotransmitter γ-aminobutyric acid (GABA), sichimangirira mwachindunji ku GABAA, GABAB, kapena benzodiazepine receptors ndipo sichikuwonjezera GABAA mu Response ya neurotransmitter, sichinasinthe kuchuluka kwa GABA mu ubongo wa makoswe, ndipo sikunakhudze kwambiri kutengeka kapena kuwonongeka kwa GABA.Komabe, kafukufukuyu adapeza kuti kuwonetsa kwanthawi yayitali kwa ma neuron otukuka ku CAS 148553-50-8 kumawonjezera kachulukidwe ka zonyamula za GABA komanso kuchuluka kwa zoyendera za GABA.CAS 148553-50-8 sichimalepheretsa njira za sodium, ilibe ntchito pa opioid receptors, sichisintha ntchito ya cyclooxygenase, ilibe ntchito pa dopamine ndi serotonin receptors, ndipo sichilepheretsa kukonzanso kwa dopamine, serotonin, kumeza.